QUALITY CONTROL AND STABILITY STUDY OF THE SODIUM
FLUORIDE INJECTION [18F]NaF

MIRELA MIHON1,2, CĂTĂLIN TUȚA2 , VASILE LAVRIC1 , DANA NICULAE2, DOINA DRĂGĂNESCU2,3*
1University Politehnica of Bucharest, Faculty of Applied Chemistry and Materials Science, 1-7 Polizu, RO-011061,
Bucharest, Romania
2“Horia Hulubei”National Institute for Physics and Nuclear Engineering, 30 Reactorului St., Magurele, Ilfov, Romania
3“Carol Davila”University of Medicine and Pharmacy, Faculty of Pharmacy, 6 Traian Vuia, RO-020956, Bucharest,
Romania
*corresponding author: doinadraganescu@yahoo.com
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Abstract:
The objective of this study was testing the stability of the radiopharmaceutical [18F]NaF solution, stored at room temperature
(15-25°C) at different time intervals. It was investigated the quality of this radiopharmaceutical substance in time under the
influence of environmental factors and the influence of material composition of septum from airtight container. The
experimental results show that the radiopharmaceutical can be considered stable up to 8 hours after the end of synthesis.






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